Age-related changes of immunological parameters in patients with collagen diseases.
نویسندگان
چکیده
منابع مشابه
Immunological aspects of age-related diseases
The proportion of elderly people rises in the developed countries. The increased susceptibility of the elderly to infectious diseases is caused by immune dysfunction, especially T cell functional decline. Age-related hematopoietic stem cells deviate from lymphoid lineage to myeloid lineage. Thymus shrinks early in life, which is followed by the decline of naïve T cells. T-cell receptor repertoi...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1988
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.11.231